![]() We show that a suboptimal regularization can produce alterations of the true image contrast in the real-valued phase-corrected images. ![]() PC effectiveness depends upon the quality of the phase estimation, which is often performed via a regularization procedure. ![]() PC finds its natural application to diffusion-weighted images (DWIs) due to their inherent low signal-to-noise ratio and consequent non-Gaussianity that induces a signal overestimation bias that propagates to the calculated diffusion indices. Phase correction (PC) is a preprocessing technique that exploits the phase of images acquired in Magnetic Resonance Imaging (MRI) to obtain real-valued images containing tissue contrast with additive Gaussian noise, as opposed to magnitude images which follow a non-Gaussian distribution, e.g.
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